Dipotassium Glycyrrhizinate-CAS 68797-35-3
Product Name: Dipotassium Glycyrrhizinate
Abbreviation: DPG
INCI Name: Dipotassium Glycyrrhizinate
CAS No.: 68797-35-3
Grade: Cosmetic Premium Grade (High-efficiency Anti-redness & Anti-allergy Special)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Uniform Fineness, Dry Without Caking, Odorless, Pure Texture Without Impurities
Molecular Formula: C₄₂H₆₀K₂O₁₆
Molecular Weight: 873.11
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent water solubility, completely and rapidly soluble in water-phase systems; insoluble in oil-phase solvents; stable in conventional cosmetic formula systems, not easy to discolor or deactivate; highly compatible with moisturizing, soothing, whitening and anti-irritation active ingredients, convenient for formula deployment and industrial mass production
Core Efficacy: Efficiently relieve skin inflammatory redness, swelling and fever sensation; inhibit inflammatory factor activity, reduce skin sensitivity and allergic reactions; repair fragile skin barrier, enhance skin tolerance; mildly inhibit melanin activity, improve inflammatory dullness and uneven skin tone; relieve skin irritation caused by acids, sun exposure and external stimulation
Key Characteristics: High-purity water-soluble salt derivative of glycyrrhizic acid; compared with traditional licorice powder, DPG has higher water solubility, faster skin penetration and quicker soothing effect; it is the mainstream and classic anti-redness and anti-allergy raw material in high-end skincare; ultra-mild, non-irritating, no sensitization; stable formula activity, not affected by pH value fluctuation, suitable for long-term barrier maintenance and sensitive skin calming
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and agglomeration, ensure stable active efficacy
Shelf Life: 24 Months
Application: Widely used in soothing toner, anti-redness essence, sensitive skin repair lotion, post-sun calming products, acid exfoliation matching skincare, anti-allergy daily care and functional brightening skincare formulas
Dipotassium Glycyrrhizinate
Dipotassium Glycyrrhizinate-CAS 68797-35-3
Cosmetic Grade Dipotassium Glycyrrhizinate (DPG) is a high-purity water-soluble licorice-derived soothing and anti-inflammatory active raw material, refined and synthesized from natural licorice effective components. As an upgraded water-soluble derivative of glycyrrhizic acid, it solves the shortcomings of traditional licorice raw materials such as poor water solubility, slow efficacy and unstable dispersion.
DPG can quickly dissolve in water-based formulas and efficiently penetrate the skin surface, rapidly inhibiting the release of internal inflammatory factors, calming skin micro-inflammation, and instantly improving redness, swelling and heat sensitivity caused by external irritation, sun exposure and cosmetic irritation.
Different from ordinary soothing ingredients that only relieve surface discomfort, DPG fundamentally regulates skin inflammatory response, reduces repeated sensitivity and redness, and repairs damaged skin barrier to improve skin tolerance.
Meanwhile, it has mild melanin inhibitory activity, which can targetedly improve inflammatory post-acne dullness and uneven skin tone, achieving dual effects of soothing repair and mild brightening. With ultra-mild properties, wide pH adaptability, no photosensitivity and excellent formula stability, Dipotassium Glycyrrhizinate is an essential core soothing and anti-redness raw material for sensitive skin care, post-procedure repair and high-efficiency calming skincare products.



Key Benefits
• High-efficiency Water-soluble, Rapid Redness Relief: Super water-soluble crystal powder, fast skin penetration, instantly calm inflammatory redness and swelling, far faster soothing efficiency than ordinary licorice raw materials.
• Root Anti-inflammation, Prevent Recurrent Sensitivity: Inhibit inflammatory factor proliferation from the source, eliminate skin micro-inflammation, solve the pain point of repeated redness and sensitivity of fragile skin, and stabilize skin state long-term.
• Barrier Repair & Improve Skin Tolerance: Repair damaged lipid barrier, reduce skin external irritation response, effectively improve fragile and sensitive skin quality, and enhance skin self-protection ability.
• Mild Inhibit Pigmentation, Improve Inflammatory Dullness: Regulate tyrosinase activity mildly, block inflammatory melanin deposition, fade acne dullness and uneven skin tone, realize repair and brightening synchronization.
• Ultra-mild & Wide pH Adaptability: Neutral and mild molecular structure, no irritation, no photosensitivity, stable activity in acidic and alkaline formulas, suitable for all skin types including sensitive skin.
• Strong Compatibility & Stable Mass Production: Perfectly compatible with water-phase formulas, stably compounded with various soothing, moisturizing and brightening ingredients, simple formula debugging, high finished product stability and qualification rate.
Applications
• Sensitive Skin Calming & Repair Series: Core soothing raw material for sensitive skin daily care, improve repeated redness, dryness and sensitivity, stabilize fragile skin barrier.
• Post-sun Redness Relief & Cooling Products: Applied in sun repair formulas, quickly relieve sunburn redness, fever and tingling, inhibit light-induced inflammation and prevent tanning dullness.
• Acid Exfoliation & Post-treatment Repair Skincare: Matched with acid skincare formulas, relieve acid irritation and redness, reduce exfoliation damage, and assist safe skin renewal.
• Anti-allergy Soothing Toner & Lotion: Added in daily moisturizing and calming products, reduce seasonal allergy discomfort, maintain skin stable and translucent state.
• Inflammatory Dullness & Acne Mark Repair Products: Used in post-acne skin care formulas, eliminate residual inflammation, fade inflammatory dullness, and uniform skin tone.
• Compound Multi-effect Skincare System: Perfectly compounded with panthenol, centella extract, beta-glucan, nicotinamide and liquorice root powder to build multi-dimensional anti-inflammation, barrier repair and brightening synergistic system.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Dipotassium Glycyrrhizinate (DPG) | Compliant |
CAS No. | 68797-35-3 | Compliant |
Appearance | White Fine Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.68% |
Loss on Drying | ≤0.5% | 0.10% |
Residue on Ignition | ≤0.1% | 0.02% |
pH Value (1% Aqueous Solution) | 6.0~8.0 | 7.1 |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Dipotassium Glycyrrhizinate?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.05%-0.2% for daily soothing maintenance products; 0.2%-0.5% for high-efficiency anti-redness and repair essence, adjustable according to product efficacy positioning.
• Q4: What is the difference between DPG and Liquorice Root Powder?
A4: DPG is high-purity water-soluble licorice salt derivative with fast dissolution and rapid redness relief, suitable for transparent water-phase products; Liquorice Root Powder is full-component herb powder with comprehensive soothing and brightening effects, suitable for cream and emulsion systems. The two can be compounded for synergistic effects.
• Q5: Is DPG suitable for sensitive skin formulas?
A5: Absolutely yes. DPG is ultra-mild, non-irritating and hypoallergenic, with excellent anti-inflammation and barrier repair effects. It is the first-choice soothing raw material for sensitive skin, pregnant skin and post-procedure repair skincare.
• Q6: What ingredients is it suitable for compounding?
A6: It can be perfectly compounded with panthenol, centella extract, beta-glucan, ellagic acid and nicotinamide to build a stable soothing, anti-redness and brightening skincare system.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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